CCB News Listing

Well done to Corrado and colleagues for their recent paper “Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint” in the journal Cell Cycle. Their work was chosen for the cover of this months edition. …

All three members of CCB’s Scientific Advisory Board made the headlines this week: John Diffley’s Nature paper on replication licensing http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11920.html Tom Misteli’s essay in Cell about cell biology of genomes http://www.cell.com/abstract/S0092-8674%2813%2900282-1 Wendy Bickmore’s review in Cell about genome architecture…

Congratulations to Prof Corrado Santocanale and to Prof Kevin Sullivan who were awarded Investigator Project Awards from Science Foundation Ireland. Corrado will continue to work on molecular mechanisms controlling DNA replication in human cells, and Kevin will study the structure…

the Lowndes lab contributes to a recent paper from Curt Wittenberg’s lab on repression of G1/S transcription. This paper has been chosen for the spotlight section of MCB, designed to highlight hot articles that are published in each issue of…

… to Dr. Elaine Dunleavy, who was recently awarded the prestigious Wellcome Trust Research Career Development Fellowship. Elaine, a former graduate of NUI Galway, will join the CCB in June this year. She will conduct her research on how gametes…

….to Tara Sugrue: the recent work of Tara, a PhD student with Noel Lowndes and Rod Ceredig (REMEDI) has been “highlighted” in the newsletter, Mesenchymal Cell News, see below.

Sugrue T, Lowndes NF*, Ceredig R*.  Mesenchymal stromal cells: radio-resistant members of the bone marrow. <http://www.ncbi.nlm.nih.gov/pubmed/23165606>  Immunol Cell Biol. 2013 Jan;91(1):5-11. doi: 10.1038/icb.2012.61. Epub 2012 Nov 20. PMID: 23165606

Sugrue T, Brown JA, Lowndes NF*, Ceredig R*.  Multiple facets of the DNA damage response contribute to the radioresistance of mouse mesenchymal stromal cell lines. <http://www.ncbi.nlm.nih.gov/pubmed/22961695>  Stem Cells. 2013 Jan;31(1):137-45. doi: 10.1002/stem.1222. PMID: 22961695

The Lahue lab and the CCB welcome new postdoctoral fellow Dr. Yanfang Ye.  She is from Fujian province, China and has conducted research in Japan, Switzerland, USA and now, Ireland.

Also from the Lahue lab: Trinucleotide repeat expansions catalyzed by human cell-free extracts. Stevens et al. Cell Research  Advance Online Publication (2013) http://www.nature.com/cr/journal/vaop/ncurrent/full/cr201312a.html