Centrosomes and the DNA damage response
A new paper from the Morrison lab highlights the involvement of the pericentriolar material in cells’ DNA damage responses. Well done to the joint first authors on this paper, Alicja and Lisa!
‘Opposing effects of pericentrin and microcephalin on the pericentriolar material regulate CHK1 activation in the DNA damage response.’
Antonczak AK, Mullee LI, Wang Y, Comartin D, Inoue T, Pelletier L, Morrison CG.
Oncogene. 2015 Jul 13. doi: 10.1038/onc.2015.257. [Epub ahead of print]