Congratulations to Andrew Flaus who co-authored a Perspective in the journal Cell on a paper by Greenberg et al. It describes how a developmental program affecting human face shape is shown to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.
Publication alert – Flaus
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